[Late-stage prosthetic valve infective endocarditis. Report of 2 cases].

Two patients with prosthetic valve infective endocarditis underwent second valve replacement after long-term medication. One patient died and the other survived. Bioprosthetic valve infection developed gradually with late appearance of valve dysfunction. We suggest surgical intervention because of poor results of medication. During the reoperation, the infected tissue should be removed thoroughly and new prosthetic valve be tightly sutured with special attention to prevention of bleeding.