Microcrystalline cellulose was the product of natural cellulose hydrolysis with diluted acid.The degree of polymerization of different raw materials and MCC made of different raw materials were tested,as well as the tablet hardness of MCC made of different raw materials.The result showed that the degree of polymerization of MCC was increased firstly,and then the bulk density was decreased as well as the tablet hardness with the increase of degree of polymerization of different raw materials.Therefore,in addition to improving the preparation conditions,MCC's selection of raw materials should be the primary