医学
马尔特淋巴瘤
病理
淋巴瘤
组织病理学
化学免疫疗法
活检
免疫组织化学
肺
淋巴系统
粘膜相关淋巴组织
边缘地带
肺活检
放射治疗
放射科
肺癌
鉴别诊断
作者
Javeeria Shabbir,Somesh Thakur,Jisha G Panicker,Krishnan E Namboothri
出处
期刊:Case Reports
[BMJ]
日期:2026-02-01
卷期号:19 (2): e269557-e269557
标识
DOI:10.1136/bcr-2025-269557
摘要
Primary pulmonary lymphoma (PPL) is a rare extranodal lymphoma confined to the lungs, accounting for <1% of non-Hodgkin lymphomas. We describe a man in his early 30s presenting with progressive dyspnoea, fever and productive cough, initially treated as pneumonia. Despite multiple antibiotic courses, radiological lesions persisted. Histopathology and immunohistochemistry from transbronchial lung biopsy revealed extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue. PET-CT confirmed localised pulmonary involvement, fulfilling criteria for PPL. The patient responded to rituximab-bendamustine chemoimmunotherapy with clinical improvement. This case highlights the importance of considering rare malignancies in non-resolving pulmonary consolidations.
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