As one of optical isomers of zeaxanthin,meso-zeaxanthin is an important ingredient of macular pigment.Compared with lutein and zeaxanthin,meso-zeaxanthin may display strong functions as antioxidant and filtering short-wavelength,for example,the blue light.Comparisons among lutein,zeaxanthin and meso-zeaxanthin as well as functions and distributions together with the source of meso-zeaxanthin were discussed.The application as a supplement of diet and issues should be studied in the future for mesozeaxanthin were also analyzed.