Biosensors Based on the Au–Se Bond

High-fidelity detection of targets with biosensors based on the Au-S bond remains challenging due to the inevitable biothiol interference. The emerging Au-Se bond-based biosensors have well resolved this concern owing to the higher stability of the Au-Se bond. This Feature highlights the developed Au-Se bond-based biosensors and discusses their design, preparation, application, current limitations, and potential future directions.