催化作用
卤键
化学
基质(水族馆)
氢键
卤素
间苯二酚
接受者
光化学
胶囊
高分子化学
分子
有机化学
地质学
烷基
物理
海洋学
生物
植物
凝聚态物理
作者
Pellegrino La Manna,Margherita De Rosa,Carmen Talotta,Antonio Rescifina,Giuseppe Floresta,Annunziata Soriente,Carmine Gaeta,Placido Neri
标识
DOI:10.1002/anie.201909865
摘要
Abstract The principle of amplified halogen bonding (XB) in a small space is exploited as a catalytic tool for the activation of an XB acceptor substrate in a nanoconfined environment. The inner cavity of the resorcinarene capsule has been equipped with an XB catalyst bearing an ammonium unit acting as a Trojan horse to drive the catalyst inside the capsule. In the presence of a specific XB catalyst, the capsule is able to catalyze a Michael reaction between N‐methylpyrrole and methyl vinyl ketone. In the bulk medium in absence of the resorcinarene capsule, the XB catalyst is catalytically ineffective. Quantum‐mechanical investigations highlight that the Michael reaction proceeds through the activation of the carbonyl group by synergistically enhanced halogen/hydrogen‐bonding interactions and takes place in an open pentameric capsule.
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