罗丹明6G
基质(水族馆)
生物传感器
拉曼散射
材料科学
拉曼光谱
胶体金
表面增强拉曼光谱
循环伏安法
分析化学(期刊)
吸附
纳米技术
化学
电化学
纳米颗粒
色谱法
分子
光学
电极
有机化学
物理化学
地质学
物理
海洋学
作者
Cheng-Ju Sung,Szu-Han Chao,Shih-Chieh Hsu
出处
期刊:Biosensors
[MDPI AG]
日期:2021-02-19
卷期号:11 (2): 54-54
被引量:7
摘要
In this report, we summarized our development of biosensors for Rhodamine 6G and in vitro glucose detection based on surface-enhanced Raman scattering technology. For the detection of both Rhodamine 6G and in vitro glucose, a nature-patterned substrate with gold films over nanostructures (NPS-AuFON) was used as the surface-enhanced Raman scattering sensor platform. The enhancement factor was calculated at 9 × 107. In the processing of the substrate, cyclic voltammetry was used to form nano-gold particles under different conditions. The Rhodamine 6G and glucose detection were then achieved on this substrate. Furthermore, we combined the potentiostatic technique and electrochemical adsorption to best detect glucose in low concentrations. The glucose oxidation potential (100 mV) was used to capture glucose close to the surface of the NPS-AuFON. The quantitative detection of glucose in solution and in situ inspection were confirmed. Further, we determined that this surface modification technology can reach the goal of experiments set by the World Health Organization to judge whether or not a patient is a diabetic by detecting a glucose concentration of 11.1 mmol/L (mg/dL) at a minimum.
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