Abstract This chapter deals primarily with the impact of social injustice on children in the United States, emphasizing children's rights in a legal context. It covers the legal status of children in society, the impact of social injustice on children's health, underlying factors and roots of this social injustice, and what needs to be done. The chapter concludes that the well-being of children depends on many investments, such as adequate family income, safe housing neighbors, and caregivers whose own lives are sufficiently supported to be able to invest time in and nurture their children. It also includes boxes on how the United States compares with other developed countries, and saving children's lives in developing countries.