Au nanoshell-coated superparamagnetic Fe 3 O 4 –silica composite nanoparticles with surface-modification of an activatable cell-penetrating peptide for tumor-targeted multimode bioimaging and photothermal therapy

The superparamagnetic Fe 3 O 4 –silica composite nanoparticles coated with Au nanoshells were prepared and subsequently surface-modified with PEG conjugated ACPP for realizing the tumor site-specific multimode bioimaging and photothermal therapy.