摘要
No AccessJournal of UrologyAdult Urology1 Jun 2017Efficacy of Electrical Pudendal Nerve Stimulation versus Transvaginal Electrical Stimulation in Treating Female Idiopathic Urgency Urinary Incontinence Siyou Wang, Jianwei Lv, Xiaoming Feng, and Tingting Lv Siyou WangSiyou Wang Clinical Research Section, Shanghai Research Institute of Acupuncture and Meridian, Shanghai, China Shanghai University of Traditional Chinese Medicine Yueyang Hospital of Traditional Chinese and Western Medicine, Shanghai, China , Jianwei LvJianwei Lv Department of Urology, Shanghai Jiaotong University School of Medicine Renji Hospital, Shanghai, China , Xiaoming FengXiaoming Feng Clinical Research Section, Shanghai Research Institute of Acupuncture and Meridian, Shanghai, China , and Tingting LvTingting Lv Department of Urology, Shanghai Jiaotong University School of Medicine Renji Hospital, Shanghai, China View All Author Informationhttps://doi.org/10.1016/j.juro.2017.01.065AboutFull TextPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissionsReprints ShareFacebookLinked InTwitterEmail Abstract Purpose: We compared the efficacy of electrical pudendal nerve stimulation vs transvaginal electrical stimulation to treat female idiopathic urgency urinary incontinence. Materials and Methods: A total of 120 female patients with idiopathic urgency urinary incontinence refractory to medication were randomized at a ratio of 2:1 to group 1 of 80 patients and group 2 of 40. Groups 1 and 2 were treated with electrical pudendal nerve stimulation and transvaginal electrical stimulation, respectively. To perform electrical pudendal nerve stimulation long acupuncture needles were deeply inserted into 4 sacrococcygeal points and electrified to stimulate pudendal nerves. Outcome measures were the 24-hour pad test and a questionnaire to measure the severity of symptoms and quality of life in women with urgency urinary incontinence. Results: The median severity of symptoms and quality of life score on the urgency urinary incontinence questionnaire (urgency urinary incontinence total score) was 13 (range 7 to 18.75) in group 1 and 11 (range 8 to 16) in group 2 before treatment, which decreased to 2 (range 0 to 6.75) in group 1 and 6.5 (range 3.25 to 10.75) in group 2 (both p <0.01) after the completion of treatment. At the end of treatment in group 1 complete symptom resolution was noted in 34 patients (42.5%), with a 50% or greater symptom improvement rate in 70.1%. In group 2 complete symptom resolution was noted in 1 patient (2.5%) with a 50% or greater symptom improvement rate in 45.0%. The posttreatment urgency urinary incontinence total score was lower and the therapeutic effect was better in group 1 than in group 2 (both p <0.01). Conclusions: Electrical pudendal nerve stimulation is more effective than transvaginal electrical stimulation in treating drug refractory, female idiopathic urgency urinary incontinence. References 1 : Refractory idiopathic urge urinary incontinence and botulinum A injection. J Urol2008; 180: 217. Link, Google Scholar 2 : Idiopathic urgency urinary incontinence. N Engl J Med2010; 363: 1156. Google Scholar 3 : Electrical neuromodulatory therapy in female voiding dysfunction. BJU Int2006; 98: 43. Google Scholar 4 : The use of electrical devices for the treatment of bladder dysfunction: a review of methods. J Urol2004; 172: 846. Link, Google Scholar 5 : Sacral neuromodulation in patients with idiopathic overactive bladder after initial botulinum toxin therapy. J Urol2013; 190: 2148. Link, Google Scholar 6 : Results of a prospective, multicenter study evaluating quality of life, safety, and efficacy of sacral neuromodulation at twelve months in subjects with symptoms of overactive bladder. Neurourol Urodyn2016; 35: 246. Google Scholar 7 : Three-year follow-up results of a prospective, multicenter study in overactive bladder subjects treated with sacral neuromodulation. Urology2016; 94: 57. Google Scholar 8 : Latest technologic and surgical developments in using InterStim therapy for sacral neuromodulation: impact on treatment success and safety. Eur Urol2008; 54: 1287. Google Scholar 9 : Complications and troubleshooting of sacral neuromodulation therapy. Urol Clin North Am2005; 32: 65. Google Scholar 10 : Alternative approaches to sacral nerve stimulation. Int Urogynecol J2010; 21: 1559. Google Scholar 11 : Chronic pudendal neuromodulation: expanding available treatment options for refractory urologic symptoms. Neurourol Urodyn2010; 29: 1267. Google Scholar 12 : Chronic pudendal nerve neuromodulation in women with idiopathic refractory detrusor overactivity incontinence: results of a pilot study with a novel minimally invasive implantable mini-stimulator. Neurourol Urodyn2005; 24: 226. Google Scholar 13 : Percutaneous tibial nerve stimulation for the long-term treatment of overactive bladder: 3-year results of the STEP study. J Urol2013; 189: 2194. Link, Google Scholar 14 : Solifenacin succinate versus percutaneous tibial nerve stimulation in women with overactive bladder syndrome: results of a randomized controlled crossover study. Gynecol Obstet Invest2013; 75: 230. Google Scholar 15 : Percutaneous tibial nerve stimulation versus tolterodine for overactive bladder in women: a randomised controlled trial. Eur J Obstet Gynecol Reprod Biol2015; 191: 51. Google Scholar 16 : Neuromodulation techniques: a comparison of available and new therapies. Curr Urol Rep2007; 8: 455. Google Scholar 17 : Simultaneous perineal ultrasound and vaginal pressure measurement prove the action of electrical pudendal nerve stimulation in treating female stress incontinence. BJU Int2012; 110: 1338. Google Scholar 18 : Long-term efficacy of electrical pudendal nerve stimulation for urgency-frequency syndrome in women. Int Urogynecol J2014; 25: 397. Google Scholar 19 : The development of a questionnaire to measure the severity of symptoms and the quality of life before and after surgery for stress incontinence. BJOG2003; 110: 983. Google Scholar 20 : Neuromodulation by implant for treating lower urinary tract symptoms and dysfunction. Eur Urol1999; 36: 81. Google Scholar 21 : The bion device: a minimally invasive implantable ministimulator for pudendal nerve neuromodulation in patients with detrusor overactivity incontinence. Urol Clin North Am2005; 32: 109. Google Scholar 22 : A new minimally invasive procedure for pudendal nerve stimulation to treat neurogenic bladder: description of the method and preliminary data. Neurourol Urodyn2005; 24: 305. Google Scholar 23 : Pudendal nerve neuromodulation with neurophysiology guidance: a potential treatment option for refractory chronic pelvi-perineal pain. Int Urogynecol J2010; 21: 613. Google Scholar © 2017 by American Urological Association Education and Research, Inc.FiguresReferencesRelatedDetails Volume 197Issue 6June 2017Page: 1496-1501 Advertisement Copyright & Permissions© 2017 by American Urological Association Education and Research, Inc.Keywordsurinary incontinenceurinary bladdervaginapudendal nervetranscutaneous electrical nerve stimulationMetricsAuthor Information Siyou Wang Clinical Research Section, Shanghai Research Institute of Acupuncture and Meridian, Shanghai, China Shanghai University of Traditional Chinese Medicine Yueyang Hospital of Traditional Chinese and Western Medicine, Shanghai, China Equal study contribution. More articles by this author Jianwei Lv Department of Urology, Shanghai Jiaotong University School of Medicine Renji Hospital, Shanghai, China Equal study contribution. More articles by this author Xiaoming Feng Clinical Research Section, Shanghai Research Institute of Acupuncture and Meridian, Shanghai, China More articles by this author Tingting Lv Department of Urology, Shanghai Jiaotong University School of Medicine Renji Hospital, Shanghai, China More articles by this author Expand All Advertisement PDF downloadLoading ...