纳米传感器
纳米尺度
发光
纳米技术
生物相容性
金属有机骨架
镧系元素
微乳液
材料科学
生物相容性材料
化学
化学工程
肺表面活性物质
有机化学
吸附
生物医学工程
光电子学
生物化学
医学
工程类
离子
作者
Tifeng Xia,Fengliang Zhu,Ke Jiang,Yuanjing Cui,Yu Yang,Guodong Qian
出处
期刊:Dalton Transactions
[The Royal Society of Chemistry]
日期:2017-01-01
卷期号:46 (23): 7549-7555
被引量:67
摘要
The precise and real-time monitoring of localized pH changes is of great importance in many engineering and environmental fields, especially for monitoring small pH changes in biological environments and living cells. Metal-organic frameworks (MOFs) with their nanoscale processability show very promising applications in bioimaging and biomonitoring, but the fabrication of nanoscale MOFs is still a challenge. In this study, we synthesized a nanoscale mixed-lanthanide metal-organic framework by a microemulsion method. The morphology and size of the NMOF can be simply adjusted by the addition of different amounts of the CTAB surfactant. This NMOF exhibits significant pH-dependent luminescence emission, which can act as a self-referenced pH sensor based on two emissions of Tb3+ at 545 nm and Eu3+ at 618 nm in the pH range from 3.00 to 7.00. The MTT assay and optical microscopy assay demonstrate the low cytotoxicity and good biocompatibility of the nanosensor.
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