An innovative approach to close large mucosal defects post-endoscopic submucosal sissection: threads combined with endoclips

Endoscopic submucosal dissection (ESD) is an effective minimally invasive treatment for early gastrointestinal cancers, offering benefits such as larger resection areas and high cure rates [1]. However, post-ESD procedures often leave large mucosal defects, creating significant complications and obstacles for clinical closure [2] [3]. Endoclips are commonly used for closure, but they can be ineffective for large defects where direct closure is difficult [4].