Real-Time Monitoring of Food Spoilage in a Stable Gel Platform Using a Benzothiazole-Based Fluorescent Sensor

DBr-Ma, a novel benzothiazole-based fluorescent sensor modified with dicyanide groups, shows exceptional sensitivity and discrimination for biogenic amines (especially spermine/cadaverine), exhibiting a 150-fold sensitivity increase over DBr-CHO. Validated by DFT, HRMS, NMR, and spectroscopy, the gel sensor PD@Ma enables real-time monitoring of seafood spoilage, advancing food safety.