化学
烷基
卤素
肟
催化作用
电泳剂
酰胺
药物化学
组合化学
有机化学
作者
Shanshan Li,Yu-Shi Jiang,Li-Ning Chen,Dan‐Na Chen,Xue-Ling Luo,Cheng-Xue Pan,Peng-Ju Xia
出处
期刊:Organic Letters
[American Chemical Society]
日期:2023-09-14
卷期号:25 (38): 7009-7013
被引量:2
标识
DOI:10.1021/acs.orglett.3c02584
摘要
The 1,2-iminylalkylation of diazenes using alkyl iodides in combination with an O-benzoyl oxime is reported. In this transformation, O-benzoyl oxime acted as a radical precursor and XAT mediator. In addition to common alkyl iodides, other alkyl iodides such as iodomethane, iodomethane-d3, trifluoroiodomethane, ethyl difluoroiodoacetate, and iodoalkanes containing unprotected hydroxyl and amide groups can also serve as C-radical precursors in the 1,2-iminylalkylation with electrophilic diazenes as radical acceptors.
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