E2F1-induced upregulation of TROAP contributes to endometrial cancer progression.

PURPOSE: expression. METHODS: tumor growth was evaluated using a mouse xenograft model. RESULTS: . CONCLUSION: is transcriptionally activated by E2F1 and promotes EC progression by enhancing cell proliferation, metastasis, and glycolysis. The E2F1-TROAP axis may serve as a potential therapeutic target for EC treatment.