材料科学
聚乙二醇
涂层
PEG比率
润湿
粉末涂料
丙烯酸聚合物
复合材料
工业化学
聚乙烯
丙烯酸树脂
聚合物
化学工程
单体
财务
生化工程
工程类
经济
作者
R. Subramaniam,Amirul Syafiq,B. Vengadaesvaran,Muhammad Shakeel Ahmad,N.A. Rahim,Pouya Hassandarvish
出处
期刊:Journal of Polymer Engineering
[De Gruyter]
日期:2024-03-13
标识
DOI:10.1515/polyeng-2023-0263
摘要
Abstract One of the biggest problems facing medical science today is preventing viral outbreaks, which highlights the significance of research initiatives aimed at creating antimicrobial coatings for a range of products, including textiles, medical devices, and public spaces. In this study, we aimed to determine the possible antiviral effects of polyethylene glycol (PEG) coating on feline coronavirus (FCoV). The PEG coatings were synthesized by a simple mixing method with a water-based acrylic binder in different weight percentages (3, 5, 10, 15, 20, and 25 wt%). The Spearman–Karber technique was used to calculate the viral titers, which were then expressed as the tissue culture infectious dose at 50 % CPE (TCID50/ml). 20 wt% PEG could result in a 3 log 10 reduction in virus titer with an inhibition rate of approximately 99.9 % against FCoV. The increment of PEG weight percent from 0 to 25 wt% decreases the hardness and glass transition temperature of the coatings from 38.1 to 5.5 HV and 15.45 to −15.48 °C. Apart from that, the wettability analysis has revealed that PEG coating is hydrophilic with water contact angle (WCA) of around 75 ± 0.5°–85 ± 0.5°. Adding 25 wt% of PEG makes the coating to be superhydrophilic with WCA of 39.85 ± 0.5°.
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