Evaluation of phosphinic acid derivatives as reagents for amine protection in peptide synthesis
试剂
化学
胺气处理
肽
肽合成
氨基酸
组合化学
磷
有机化学
生物化学
作者
R. Ramage,Butrus Atrash,David Hopton,Maxwell J. Parrott
出处
期刊：Perkin Transactions [Royal Society of Chemistry] 日期：1985-01-01卷期号：: 1217-1217被引量：26
标识
DOI：10.1039/p19850001217
摘要
The results of a kinetic study of the acid-catalysed methanolysis of a series of N-(2-phenyl-ethyl)phosphinamides incorporating selected substituents on phosphorus have been evaluated in order to define the optimum reagent and conditions for amine protection of α-amino acids during peptide synthesis.
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