Mesangiolytic Poststreptococcal Glomerulonephritis

We describe two children with poststreptococcal glomerulonephritis associated prolonged oligoanuria (12, 13 days). Kidney biopsies at 10 and 6 days, respectively, revealed acute glomerulonephritis with prominent mesangiolysis. Both patients recovered uneventfully. It is proposed that damage to the mesangium accounts for the clinical course.