低尿酸血症
苯溴马隆
尿酸
医学
吡嗪酰胺
癌症
内科学
重吸收
化疗
肿瘤科
胃肠病学
泌尿科
高尿酸血症
病理
肾
异烟肼
肺结核
作者
Manuel Morales,Víctor García‐Nieto
出处
期刊:Oncology
[S. Karger AG]
日期:1996-01-01
卷期号:53 (4): 345-348
被引量:6
摘要
Two cases of hypouricemia in association with malignant diseases are presented. One patient had metastatic breast cancer and the other an undifferentiated retroperitoneal sarcoma of the childhood. Uric acid renal handling was studied with the pyrazinamide and benzbromarone tests. Both patients had reduced postsecretory reabsorption of uric acid. The increase of serum uric acid levels in both patients, after a partial response to chemotherapy, indicates the possible paraneoplastic origin of hypouricemia. Our results are discussed and compared with other reports in the literature.
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