Ethanol and water extraction technology about total flavones of Hippophe rhamnoids Linn(TFH) in leaves was screened by orthogonal experiment.The best ethanol extraction technology was determined as follows: at 70 ℃ for 2 h,1.5 h with 50 % ethanol in two ethanol extraction process.The best water extraction technology was determined as follows: circling extraction for 2 h,1.5 h with volume of water 100 mL,80 mL in two water extraction.The extraction yield of TFH is 1.258 2 % by ethanol extraction and 0.927 8 % by water extraction.