Objective To conduct multivariate conditional Logistic regression model.Methods A case-control study was conducted on 150 cases and their controls.The self-designed questionnaires were used for collecting data.Multivariate conditional Logistic regression was used to analyze risk factors.Results Factors that were entered model included home decoration,busy roads nearby and chemical plant.Conclusion The occurrence of malign blood system disease is related to home and environmend air pollution.