A controlled study of aripiprazole and risperidone in treatment of schizophrenia

Objective To compare the efficacy and safety of aripiprazole and risperidone in the treatment of schizophrenia.Methods 60 patients with schizophrenia were randomly divided into two groups: aripiprazole group(n=30) and risperidone group(n=30).The therapeutic effects were evaluated by PANSS,and side effects were assessed by TESS before and after 2,4,6 and 8 treatment weeks.Results The rates of marked improvement in aripiprazole group and risperidone group were 76.7% and 73.3%,respectively.Conclusion Both aripiprazole and risperidone have good effective in the treatment of schizophrenia.But aripiprazole has less adverse effects.It's an effective and safe antipsychotic drug.