Objective To evaluate the clinical performance of ceramic inlays, Au alloy inlays and polymeric porcelain inlays in restoring the molar defect. Methods According to the materials chosen by patients,197 cases selected with indications were divided into four groups:47 cases for ceramic inlays,47 cases for Au alloy inlays, 50 cases for polymeric porcelain inlays and 53 cases for composite resin. All restorations were evaluated after half a year according to modified USPHS parameters. Results No statistically significant difference was shown for gingival status between three inlays,and there was significant difference between inlays groups and composite resin group. Conclusion It is an intriguing method using inlays to restore the molar defect,which is superior to restoration in the aspects of maintaining periodontal health.