适体
DNA
运动性
化学
体外
癌细胞
癌症研究
转移
细胞
C-Met公司
分子生物学
癌症
细胞生物学
生物化学
生物
肝细胞生长因子
遗传学
受体
作者
Ryosuke Ueki,Shinsuke Sando
摘要
The HGF/c-Met pathway is known to play a key role in cancer metastasis. CLN0003_SL1, a 50-mer DNA aptamer that binds to the c-Met protein, was found to inhibit HGF-induced c-Met activation. This aptamer could suppress cancer cell motility in vitro.
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