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Effect of moxibustion on ureteral stent-related symptoms after ureteroscopic lithotripsy.

医学 艾灸 坦索罗辛 安慰剂 下尿路症状 泌尿系统 外科 针灸科 泌尿科 内科学 前列腺 替代医学 病理 癌症 增生
作者
Hao Chen,Yun Wang,Zhimin Wang,Yu Zhang,R. J. Zhao
出处
期刊:PubMed 卷期号:43 (11): 1251-1256
标识
DOI:10.13703/j.0255-2930.20230422-k0001
摘要

To observe the clinical efficacy of moxibustion combined with western medication on ureteral stent-related symptoms after ureteroscopic lithotripsy (URL).One hundred and fifty patients with upper urinary tract calculus implanted with ureteral stents after URL were randomly divided into a moxibustion group (50 cases, 1 case dropped out), a placebo moxibustion group (50 cases, 3 cases dropped out) and a blank control group (50 cases). No intervention was performed in the blank control group. On the basis of oral administration with tamsulosin hydrochloride sustained release capsule (starting from the first day after surgery, once a day, 0.2 mg each time, continuously for 4 weeks), in the moxibustion group, moxibustion was operated at Guanyuan (CV 4) and bilateral Shenshu (BL 23); the sham-moxibustion was delivered at the same acupoints in the placebo moxibustion group, once daily, 6 times a week, for 15 min in each treatment. The duration of treatment was 4 weeks. Before treatment, and after 1, 2 and 4 weeks of treatment, the scores of lower urinary tract symptoms, body pain, general health, work performance and satisfaction of sexual matters were compared among the 3 groups. The tract calculus clearance rate, urinary infection and the oral administration of painkillers were compared after 4 weeks of treatment in the 3 groups.The scores of lower urinary tract symptoms, body pain and general health after 1 week of treatment, and the scores of lower urinary tract symptoms, body pain, general health and work performance after 2 and 4 weeks of treatment were lower than those before treatment in the 3 groups (P<0.01). The scores of lower urinary tract symptoms and body pain in the moxibustion group after 1, 2 and 4 weeks of treatment were lower than those in the blank control group and the placebo moxibustion group (P<0.01, P<0.05) respectively. The score of general health in the moxibustion group was lower than that in the blank control group after 1 week of treatment (P<0.01), and lower than those of the blank control group and the placebo moxibustion group after 2 and 4 weeks of treatment (P<0.01, P<0.05). Regarding the score of work performance, it was lower in the moxibustion group after 1 and 2 weeks of treatment compared with those in the blank control group (P<0.05, P<0.01), and lower than those of the blank control group and the placebo moxibustion group after 4 weeks of treatment (P<0.01, P<0.05). The tract calculus clearance rate in the moxibustion group was 95.9% (47/49), higher than that in the blank control group (80.0%, 40/50, P<0.05). The proportion of oral administration of painkillers in the moxibustion group (28.6%, 14/49) and the placebo moxibustion group (40.4%, 19/47) was lower than that in the blank control group (76.0%, 38/50, P<0.01) respectively.Moxibustion combined with western medication relieves lower urinary tract symptoms and body pain, and accelerate the recovery of general health and work performance in the patients after URL.目的: 观察艾灸联合西药治疗输尿管镜碎石术(URL)后输尿管支架管综合征(USS)的临床疗效。方法: 将150例URL术后置入输尿管支架管的上尿路结石患者随机分为艾灸组(50例,脱落1例)、安慰艾灸组(50例,脱落3例)和空白对照组(50例)。空白对照组不行任何干预。在口服盐酸坦索罗辛缓释胶囊(术后第1天开始,每次0.2 mg,每日1次,连续治疗4周)基础上,艾灸组艾灸关元、双侧肾俞,安慰艾灸组采用假艾灸相同穴位,均每次15 min,每日1次,每周6次,共治疗4周。比较各组患者治疗前及治疗1、2、4周后下尿路症状、身体疼痛情况、一般情况、工作能力、性生活满意度评分,比较各组治疗4周后结石清除率及尿路感染、口服止痛药情况。结果: 各组治疗1周后下尿路症状、身体疼痛情况、一般情况评分及治疗2、4周后下尿路症状、身体疼痛情况、一般情况、工作能力评分均较治疗前降低(P<0.01)。艾灸组治疗1、2、4周后下尿路症状、身体疼痛情况评分低于空白对照组及安慰艾灸组(P<0.01,P<0.05)。艾灸组治疗1周后一般情况评分低于空白对照组(P<0.01),治疗2、4周后低于空白对照组及安慰艾灸组(P<0.01,P<0.05)。艾灸组治疗1、2周后工作能力评分低于空白对照组(P<0.05,P<0.01),治疗4周后低于空白对照组及安慰艾灸组(P<0.01,P<0.05)。艾灸组结石清除率为95.9%(47/49),高于空白对照组的80.0%(40/50,P<0.05)。艾灸组(28.6%,14/49)和安慰艾灸组(40.4%,19/47)口服止痛药比例低于空白对照组(76.0%,38/50,P<0.01)。结论: 艾灸联合西药可缓解URL术后患者下尿路症状及身体疼痛,加快一般情况及工作能力恢复。.

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