串扰
生物
中枢神经系统
神经科学
神经组织
神经系统
外周神经系统
电池类型
平衡
淋巴系统
神经胶质
脂肪组织
细胞生物学
细胞
免疫学
内分泌学
物理
光学
遗传学
作者
Gilian Gunsch,Emma Paradie,Kristy L. Townsend
标识
DOI:10.1016/j.tem.2023.07.004
摘要
The peripheral nervous system (PNS) relays information between organs and tissues and the brain and spine to maintain homeostasis, regulate tissue functions, and respond to interoceptive and exteroceptive signals. Glial cells perform support roles to maintain nerve function, plasticity, and survival. The glia of the central nervous system (CNS) are well characterized, but PNS glia (PNSG) populations, particularly tissue-specific subtypes, are underexplored. PNSG are found in large nerves (such as the sciatic), the ganglia, and the tissues themselves, and can crosstalk with a range of cell types in addition to neurons. PNSG are also subject to phenotypic changes in response to signals from their local tissue environment, including metabolic changes. These topics and the importance of PNSG in metabolically active tissues, such as adipose, muscle, heart, and lymphatic tissues, are outlined in this review.
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