Effects of fluorescein on corneal endothelial morphology after fundus fluorescein angiography in patients with diabetic macular edema

眼科 医学 荧光素眼底血管造影 眼底(子宫) 糖尿病性视网膜病变 荧光素 荧光血管造影 黄斑水肿 眼压 视力 变异系数 糖尿病 内分泌学 化学 荧光 色谱法 物理 量子力学
作者
Utku Limon,Işılay Özsoy Saygın,Tuğba Aydoğan Gezginaslan,Erdinç Bozkurt,Sinan Bulut,Betül İlkay Sezgin Akçay
出处
期刊:Cutaneous and Ocular Toxicology [Taylor & Francis]
卷期号:42 (3): 91-96
标识
DOI:10.1080/15569527.2023.2215346
摘要

AbstractAbstractPurpose To evaluate the effects of fluorescein dye on corneal endothelial morphology (CEM) after fundus fluorescein angiography (FFA) in patients with diabetic macular edema (DME).Methods In this retrospective study, patients were divided into two groups, nonproliferative diabetic retinopathy (Group-1, NPDR) and proliferative diabetic retinopathy (Group-2, PDR). CEM properties including endothelial cell density (ECD), coefficient of variation of cell area (CV), average cell area (AVG), percentage of hexagonal cells (HEX), and central corneal thickness (CCT) were measured before FFA and at week 1 and month 1 after FFA were collected from patients’ charts.Results The study consisted of 48 patient’s 48 eyes in Group-1 and 50 patient’s 50 eyes in Group-2. In both groups, the mean ECD, CV, AVG, HEX, and CCT measurements at week 1 and month 1 after FFA did not differ statistically from the mean measurements before FFA (p > 0.05). The mean ECD measurements in Group-1 were higher than that in Group-2 and showed statistically significant differences among the groups (p < 0.01 for all). In the Pearson correlation analysis in Group-1, there was no statistically significant relationship between best-corrected visual acuity (BCVA) and (intraocular pressure) IOP values and ECD, AVG, CV, HEX, and CCT measurements (except central macular thickness [CMT] and HEX) before FFA, at week 1 and month 1 after FFA (p > 0.05). In Group-2 there was no statistically significant relationship between BCVA, IOP, and CMT measurements and ECD, AVG, CV, HEX, and CCT measurements before FFA, at week 1 and month 1 after FFA (p > 0.05).Conclusions There is no significant change in CEM after FFA in patients with NPDR and PDR with DME.Keywords: Fluorescein dyecorneal endothelial morphologydiabetic macular edema Disclosure statementNo potential conflict of interest was reported by the authors.Ethical approvalThe study protocol was approved by the local ethics committee in the University of Health Sciences Umraniye Training and Research Hospital Eye Clinic Istanbul/Turkey.Additional informationFundingThis study did not receive any financial supports.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
刚刚
戴岱完成签到,获得积分10
4秒前
算的发布了新的文献求助10
4秒前
失眠的香蕉完成签到 ,获得积分10
5秒前
眼睛大的寄容完成签到 ,获得积分10
7秒前
加薪奥利奥完成签到 ,获得积分10
8秒前
42完成签到 ,获得积分10
11秒前
你怎么睡得着觉完成签到,获得积分10
11秒前
dx完成签到,获得积分10
12秒前
专注灵凡完成签到,获得积分10
12秒前
七子完成签到,获得积分10
14秒前
zzx396完成签到,获得积分10
15秒前
共享精神应助科研通管家采纳,获得10
17秒前
debu9完成签到,获得积分10
17秒前
科研通AI5应助科研通管家采纳,获得10
17秒前
tianshanfeihe完成签到 ,获得积分10
17秒前
香蕉觅云应助科研通管家采纳,获得10
17秒前
墨痕mohen完成签到,获得积分10
18秒前
Muhi完成签到,获得积分10
18秒前
QIQI完成签到,获得积分10
20秒前
21秒前
21秒前
su完成签到 ,获得积分10
26秒前
Eric完成签到,获得积分10
28秒前
谢陈完成签到 ,获得积分10
30秒前
DD立芬完成签到 ,获得积分10
34秒前
40秒前
呆萌芙蓉完成签到 ,获得积分10
43秒前
朱科源啊源完成签到 ,获得积分10
44秒前
任盈盈完成签到,获得积分10
45秒前
46秒前
Rousongxiaobei完成签到,获得积分10
54秒前
李梦媛完成签到 ,获得积分10
56秒前
科研小白完成签到 ,获得积分10
1分钟前
nakl完成签到,获得积分10
1分钟前
song完成签到 ,获得积分10
1分钟前
1分钟前
二世小卒完成签到 ,获得积分10
1分钟前
开心完成签到 ,获得积分10
1分钟前
OIIII完成签到,获得积分10
1分钟前
高分求助中
【此为提示信息,请勿应助】请按要求发布求助,避免被关 20000
Continuum Thermodynamics and Material Modelling 2000
Encyclopedia of Geology (2nd Edition) 2000
105th Edition CRC Handbook of Chemistry and Physics 1600
Maneuvering of a Damaged Navy Combatant 650
Периодизация спортивной тренировки. Общая теория и её практическое применение 310
Mixing the elements of mass customisation 300
热门求助领域 (近24小时)
化学 材料科学 医学 生物 工程类 有机化学 物理 生物化学 纳米技术 计算机科学 化学工程 内科学 复合材料 物理化学 电极 遗传学 量子力学 基因 冶金 催化作用
热门帖子
关注 科研通微信公众号,转发送积分 3779296
求助须知:如何正确求助?哪些是违规求助? 3324813
关于积分的说明 10220097
捐赠科研通 3039971
什么是DOI,文献DOI怎么找? 1668528
邀请新用户注册赠送积分活动 798717
科研通“疑难数据库(出版商)”最低求助积分说明 758503