微泡
外体
细胞外小泡
生物
计算生物学
病毒学
免疫学
细胞生物学
基因
小RNA
遗传学
作者
Manica Negahdaripour,Bahare Vakili,Navid Nezafat
标识
DOI:10.1016/j.intimp.2022.109265
摘要
Extracellular vesicles (EVs), which include exosomes as a subset, are generated by most cell types and play crucial roles in intercellular communication. Exosomes offer intriguing tools as potential vaccines due to their ability to deliver a wide range of antigens and immunomodulatory properties. Exosome-based vaccines have demonstrated promising results against different types of infectious diseases as well as cancers, both in vitro and in vivo. In this review, a number of studies on exosome-based vaccines are highlighted and relevant clinical trials are discussed.
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