Bioeliminable Pt@Bi2Se3-RGD Nanoassembly for Enhancing Photoacoustic Imaging-Guided Tumor Immuno-Radiotherapy by Inducing Apoptosis via the Areg Pathway

The multifunctional, bioeliminable PBR nanoassembly synthesized in this study demonstrated radiosensitization, which, in conjunction with the PD-L1 immune blockade, could suppress primary and distal tumors. Thus, as a sensitizer for synergistic radiotherapy and immunotherapy, PBR could have wide-ranging clinical applications in oncology.