肝细胞癌
医学
突变
癌症研究
桑格测序
生物
基因
遗传学
作者
Rongqi Sun,Kaixuan Liu,Si-Yuan Pan,Yuhang Ye,Ning Li,Shuangyi Chen,Xinyi Cui,Yuxi Zhang,Long Chen,Jingyue Pan,Zhiqiang Hu,Chu‐Bin Luo,Jia Fan,Zheng‐Jun Zhou,Shao‐Lai Zhou,Jian Zhou
出处
期刊：Hepatology
[Lippincott Williams & Wilkins]
日期：2024-12-24
卷期号：82 (5): 1073-1089
被引量：4
标识
DOI：10.1097/hep.0000000000001212
摘要
Our results identified novel LRP4 mutations important in recurrent HCC. Inactivating LRP4 mutations were associated with resistance to anti-programmed cell death protein-1 therapy and could be useful biomarkers for precision therapy in patients with recurrent HCC.
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(2025-6-4)
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