Cold Versus Hot Endoscopic Mucosal Resection for ≥15 mm Large Nonpedunculated Colorectal Polyps

Our analysis shows that C-EMR is a cost-effective strategy compared with H-EMR for LNPCPs ≥15 mm. While H-EMR offers lower recurrence rates, its higher rates of adverse events-such as DPPB and perforation-contribute to increased costs and reduced overall effectiveness.