多巴胺
神经形态工程学
突触可塑性
神经科学
神经递质
刺激(心理学)
材料科学
计算机科学
化学
生物
人工神经网络
人工智能
心理学
中枢神经系统
生物化学
受体
心理治疗师
作者
Jie Qian,Jie Cao,Xusheng Liu,Pei Chen,Feng Gao,Xumeng Zhang,Ming Wang,Qi Liu
出处
期刊:IEEE Electron Device Letters
[Institute of Electrical and Electronics Engineers]
日期:2023-01-01
卷期号:44 (1): 176-179
被引量:9
标识
DOI:10.1109/led.2022.3225143
摘要
Artificial synapses relying on electrical and optical stimuli to implement neuromorphic tasks have been intensively developed, but very few of them can directly respond to real biological neurotransmitter stimulus, thus limiting the seamless integration of bio-electronic interfaces. In this letter, we report a flexible organic electrochemical transistor-based synaptic device, which demonstrates not only short-term synaptic behaviors dominated by the kinetics of ions but also long-term synaptic behaviors derived from the redox reaction of dopamine neurotransmitters. More importantly, we systematically studied the dopamine-mediated synaptic plasticity under both flat and bending states, which shows reliable synaptic response and excellent mechanical flexibility. These results reveal that our device providing a promising way for direct biohybrid integration with soft biological tissues.
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