作者
Petros Grivas,Elena Garralda,Funda Meric‐Bernstam,Ingo K. Mellinghoff,Lipika Goyal,James J. Harding,Elizabeth Claire Dees,Rastislav Bahleda,Nilofer S. Azad,Asha Karippot,Razelle Kurzrock,Josep Tabernero,Juha Kononen,Matthew Chau Hsien Ng,Rutika Mehta,Nataliya V. Uboha,Frédéric Bigot,Valentina Boni,Samantha E. Bowyer,В. В. Бредер,Andrés Cervantes,Nancy Chan,James M. Cleary,Mallika Dhawan,Rikke Løvendahl Eefsen,James Ewing,Donna M. Graham,Tormod K. Guren,Jin Won Kim,Krassimir Koynov,Do‐Youn Oh,Rebecca Redman,Chia‐Jui Yen,David Spetzler,Marie-Claude Roubaudi-Fraschini,Valerie Nicolas-Metral,Rafik Ait-Sarkouh,Claudio Zanna,Abdallah Ennaji,Anna Pokorska-Bocci,Keith T. Flaherty
摘要
This multicenter phase II basket trial investigated the efficacy, safety, and pharmacokinetics of Debio 1347, an investigational, oral, highly selective, ATP-competitive, small molecule inhibitor of FGFR1-3, in patients with solid tumors harboring a functional FGFR1-3 fusion.
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