静电纺丝
壳聚糖
扫描电子显微镜
共焦
纤维
聚合物
共焦激光扫描显微镜
材料科学
化学工程
形态学(生物学)
场发射显微术
共焦显微镜
复合材料
化学
生物医学工程
光学
衍射
医学
物理
生物
工程类
遗传学
作者
Jau-Yang Chang,Yen Hsien Lee,Meng Hsiu Wu,Ming Yang,Chiang Ting Chien
标识
DOI:10.1016/j.carbpol.2011.10.054
摘要
In this study, alginate (AL) fibers were electrospun and coagulated with chitosan (ChS) and ethanol using a single spinneret. These fibers exhibited a core–sheath structure that was revealed using a confocal laser scanning microscope (CLSM) and fluorescence-labeled polymers. The resulting fibers were examined using a field emission scanning electron microscope (FESEM) for the fiber size and morphology. The average diameter of the fibers ranged from 600 to 900 nm depending on the electrospinning parameters. To mimic the stability of alginate fibers in physiological fluids, the release of alginate from these fibers in normal saline was also tested. The results demonstrated that the core–sheath structure of alginate fiber can greatly reduce the degradation by 40% for 3 d in physiological environment.
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