The Multimodal Cyclodextrin Bonded Stationary Phases for High Performance Liquid Chromatography

Abstract The use of α-, β-, and γ-cyclodextrin bonded stationary phases as multimodal support in HPLC is discussed. These supports are being used as reversedphase and normal phase for the separation of widely different groups of compounds. Also, they are used as for the separation of optical, geometrical, positional and structural isomers in addition to ions and organo-metallic compounds. A brief discussion of separation mechanisms and application and their use with other stationary phases to improve selectivity are also presented.