重新调整用途
药物重新定位
癌症治疗
更安全的
医学
癌症
抗癌药物
重症监护医学
癌症治疗
药品
风险分析(工程)
计算机科学
药理学
内科学
工程类
计算机安全
废物管理
作者
Aurora González-Fierro,Alfonso Dueñas‐González
标识
DOI:10.1016/j.semcancer.2019.12.012
摘要
Drug repurposing for cancer therapy is currently a hot topic of research. Theoretically, in contrast to the known hurdles of developing new molecular entities, the approach of repurposing has several advantages. Mostly, it is said that it is faster, safer, easier, and cheaper. In the real world, however, there are only three repurposed drugs so far, that are listed in widely recognized cancer guidelines, but a large number of them are being studied. Among the many barriers to repurposing cancer drugs, economical-driven are the most important that difficult the clinical development of them. In this review, we provide an overview of the current status of drug repurposing for cancer therapy and the barriers that need to be overcome to realize the benefit of this approach. It means to have repositioned drugs for cancer therapy accepted as standard therapy for cancer indications at low cost.
科研通智能强力驱动
Strongly Powered by AbleSci AI