小切口晶状体摘除术
激光手术
角膜磨镶术
医学
眼科
去神经支配
前瞻性队列研究
角膜地形图
光学相干层析成像
角膜
外科
解剖
作者
Anastasios John Kanellopoulos
出处
期刊:Cornea
[Ovid Technologies (Wolters Kluwer)]
日期:2018-12-05
卷期号:38 (3): 290-296
被引量:30
标识
DOI:10.1097/ico.0000000000001821
摘要
Purpose: To evaluate 3-dimensional epithelial remodeling in patients undergoing myopic laser in situ keratomileusis (LASIK) versus small incision lenticule extraction (SMILE). Methods: In a prospective randomized contralateral eye study of LASIK versus SMILE procedures, 21 consecutive patients (42 eyes) were evaluated with corneal epithelial mapping by anterior segment optical coherence tomography for up to 2 years. Results: In the LASIK group, central epithelial thickness increased from 52.38 ± 2.57 μm to 57.00 ± 4.23 μm and remained almost stable at this level for up to 24 months. In the SMILE eyes, it increased from 52.52 ± 3.01 μm to 57.15 ± 4.57 μm and also remained stable for up to 24 months. Both techniques created the same level of epithelial thickness increase and variation, with a significantly higher mid-peripheral epithelial thickness increase. The differences between the preoperative and postoperative changes were found statistically significant, but not different between the 2 techniques at any given time studied. Conclusions: Both LASIK and SMILE resulted in significant epithelial thickening. This response seemed to be surprisingly quite similar between the 2 different techniques. This study suggests that epithelial remodeling may correlate with relative curvature changes resulting after both techniques, rather than the obvious difference of subepithelial corneal denervation changes.
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