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Effect of resistance exercises with calcium consumption on level of anti-mullerian hormone and some metabolic indices in women with polycystic ovarian syndrome

医学 胰岛素抵抗 多囊卵巢 内科学 代谢综合征 抗苗勒氏激素 内分泌学 不育 安慰剂 排卵 妇科 激素 胰岛素 肥胖 怀孕 生物 替代医学 病理 遗传学
作者
Abbas Saremi,Mohadaseh Sadat Yaghoubi
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摘要

Introduction: Polycystic ovary syndrome (PCOS) is one of the most common endocrinal disorders in women at reproductive age. In many cases, PCOS is associated with infertility and increased risk of metabolic syndrome. This study was performed with aim to investigate the effect of 8-week resistance exercise and calcium supplementation on anti-mullerian hormone (AMH) level and metabolic parameters in women with PCOS. Methods: This semi-experimental study was performed with pretest–posttest design on 30 women with PCOS who were referred to one of the medical centers of Arak in 2014. They were randomly assigned to three groups of resistance exercise and placebo, resistance exercise and calcium supplementation consumption (1000 mg/d), and control with 10 cases in each group. The protocol consisted of 3 sessions per week of exercise for 8 weeks, each session including 1-2 sets of 5–20 repetitions at 40–60 of 1RM(one repetition maximum). Serum levels of AMH and metabolic parameters were assessed before and after the training period. Data were analyzed using SPSS software (version 18), and two-way ANOVA and ANCOVA tests. PResults: After 8 week total cholesterol resistance exercise, LDL-c, triglycerides and insulin resistance index were significantly decreased (P<0.05). Data analysis showed that calcium supplementation in conjunction with resistance exercise leads to more improvement in metabolic indices and serum level of AMH (P<0.05). Conclusion: Resistance training in conjunction with calcium supplementation for two months can have beneficial effects on metabolic indices and ovarian reserve in women with PCOS.

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