接触性荨麻疹
接触性皮炎
医学
皮肤病科
化妆品
过敏性接触性皮炎
刺激性接触性皮炎
过敏
病理
免疫学
作者
Ana Giménez‐Arnau,Marcus Maurer,J. de la Cuadra,Howard I. Maibach
出处
期刊:PubMed
日期:2010-08-25
卷期号:20 (5): 552-62
被引量:26
标识
DOI:10.1684/ejd.2010.1049
摘要
Listening and paying attention to our patients is crucial for understanding a disease. A good example is Immediate Contact Skin Reactions (ICSR) which manifest as Contact Urticaria Syndrome (CUS), Contact Urticaria (CU) and Protein Contact Dermatitis (PCD). These entities are characterized by the immediate skin development of itchy flares, wheals, and/or dermatitis. All conditions usually appear within minutes of contact with various substances, including chemicals, animal products, antibiotics, cosmetics, and many other materials. From the clinical and diagnostic viewpoint, the patient's clinical report is critical to its description, definition and classification. Its pathogenesis still remains a challenge and our knowledge of the agents potentially responsible is slowly increasing over time, based on the descriptions of a few isolated cases. This text reviews the classic concepts, introduces new compounds responsible for these immediate skin reactions, and suggests further investigation.
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