Most of functional magnetic resonance imaging(fMRI)studies have employed task-related paradigm in exploration of brain response to an external stimulus.However,recent studies have found that the brain is very active in resting-state.Resting-state functional magnetic resonance imaging(resting-state fMRI)is a relatively new method that can reflect the brain complicated activity and provide a new method for exploring the interner mechanismus of brain activity fully,it has achieved greater development in the study of neuropsychiatric diseases.Its experimental design can simulate the actual course of acupuncture treatment basically,therefore it has the huge potential in the research of acupuncture′s nerve mechanism domain.