Biological Markers or Biomarkers are useful tool in studies of environmental exposure to volatile organic compounds (VOCs) on human beings This article is a review with 37 references It is presented on the all kinds of Biomarkers including biomarker of exposure, biomarker of effect and biomarker of susceptibility The relationship among biomarkers is also discussed in this paper It introduced the current progress and application of biomarkers in environmental health fields The effect of VOCs on human beings is also discussed