The Impact of the content of thioglycolic acid on perm solution curls effect was studied.The results show that the difference in pH value more appropriate range of 8 to 9,when thioglycolic acid content is less than 2%of without impact,of 6%to 7%,have best.The effect of more than 7%curls deteriorated.The accurate determination of the content of the perm solution of thioglycolic acid(TGA) of the detection method of the titration,in order to find the influence perm effect the main ingredient thioglycolic acid content.