Treatment of congestive heart failure with low-dose spironolactone

Objective To evaluate the clinical efficacy of low-dose spironolactone treatment on congestive heart failure (CHF).Methods 52 patients received low-dose spironolactone 20～40 mg a day for 8 weeks,with the routine treatment.Results Compared with those in control group,EF volume, stroke volume in spironolactone treatment group were significantly increased.In Addition, the clinical manifestations were also improved in spironolactone treatment group (P0.05).Conclusion [WTBZ]The low-dose spironolactone is effective in treating congestive heart failure,which could improve clinical manifestation and the heart function,which also could decrease the mortality.