Review of the British Thoracic Society Winter Meeting 26–29 November 2025

BACKGROUND: The 2025 British Thoracic Society (BTS) Winter Meeting delivered 3 days of cutting-edge science, clinical innovation and networking in wintry Westminster. Over 2500 attendees from 36 countries gathered to share advances shaping the future of respiratory medicine. CONTENT: The programme opened with a session focused on emerging clinical trial data, showcasing pragmatic and mechanistic studies designed to address real-world challenges in respiratory care, setting the tone for a meeting focused on impact and innovation.Translational research featured strongly throughout the meeting, with organoids, precision-cut lung slices and air-liquid interface cultures providing new perspectives on disease mechanisms and therapeutic targets. Early career investigators presented discoveries in eosinophilic chronic obstructive pulmonary disease biology, microbiome-driven viral susceptibility and resistance risks in novel bronchiectasis therapies, while midcareer leaders advanced understanding of familial interstitial lung disease and virus-host interactions.Plenary sessions tackled pressing challenges, from air pollution and breathlessness diagnostics to genetic drivers of pulmonary hypertension, complemented by guest lectures on immune regulation, vaccine-preventable illness and drug discovery. Additionally, the meeting highlighted workforce transformation, emphasising the role of nurses, allied health professionals and pharmacists in delivering integrated, digitally enabled care. CONCLUSION: Reminding us that progress rests on both scientific endeavour and enduring professional bonds, the 2025 BTS Winter Meeting reaffirmed that respiratory research is for everyone-an essential driver of advancement across disciplines. Multidisciplinary working and inclusive engagement will be key to shaping future care and ensuring that innovation translates into better outcomes for patients worldwide.