Organocatalytic aminocarbonylation of α,β-unsaturated ketones with N,N-dimethyl carbamoylsilane
化学
药物化学
催化作用
有机化学
作者
Shou-Shan Yang,Ying-Zheng Ren,Yuyu Guo,Guang-Fen Du,Zhihua Cai,Lin He
出处
期刊:New Journal of Chemistry [The Royal Society of Chemistry] 日期:2021-04-26卷期号:45 (16): 7256-7260被引量:2
标识
DOI:10.1039/d1nj00782c
摘要
An organic superbase-catalyzed aminocarbonylation reaction of α,β-unsaturated ketones was reported. Under the catalysis of 10 mol% Schwesinger's superbase t-Bu-P4, a variety of enones and ynones reacted with N,N-dimethyl carbamoylsilane to afford α-siloxyamides or α-hydroxyamides in 56–82% yields.