医学
神经营养素
眼科
神经科学
神经营养因子
心理学
内科学
受体
作者
Guillermo Raúl Vera Duarte,David Jimenez-Collado,Nicolás Kahuam-López,Arturo Ramírez-Miranda,Enrique O Graue-Hernández,Alejandro Navas,Mark I. Rosenblatt
标识
DOI:10.1016/j.survophthal.2024.04.004
摘要
Abstract
Neurotrophic keratopathy is an uncommon degenerative corneal disorder characterized by compromised corneal sensory innervation, resulting in the formation of epithelial defects and nonhealing corneal ulcers. Various treatment modalities are available to stabilize disease progression, improve patient well-being, and prevent vision loss. For eligible patients, medical and surgical reinnervation have emerged as pioneering therapies, holding promise for better management. This article presents a comprehensive review of the disease, providing an update relevant to ophthalmologists on pathogenesis, diagnosis, treatment options, and novel therapies targeting pathophysiological pathways.
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