A New Process for the Bromination of Aromatic Amines and Phenols

A new process for the Brominations of aromatic amines and phenols was reported. The reactions were carried out at room temperature with CHCl3, EtOH or EtOH/CHCl3 as solvent, selective monobromination of some aromatic amines and phenols occurred(five substrates were investigated) at a ratio of N-bromosuccinimide to substrate 1∶1, the yields were 92%~98%. Dibromination of some aromatic amines and phenols occur smoothly(five substrates were investigated), at a ratio of N-bromosuccinimide to substrate 2∶1, the yields were 90%~97%. As a green and environmentally benign method, the Brominations of aromatic amines and phenols could be achieved at room temperature without using catalysts. In addition, the final products could be collected after filtration and washing process.