X‐Ray‐Responsive Zeolitic Imidazolate Framework‐Capped Nanotherapeutics for Cervical Cancer‐Targeting Radiosensitization (Adv. Funct. Mater. 13/2023)

Cervical Cancer-Targeting Radiosensitization In article number 2213364, Xueqiong Zhu, Tianfeng Chen, and co-workers report zeolitic imidazolate framework-capped Mn3O4 nanoparticles modified with folic acid with X-ray response properties. This nanoparticle possesses a high oxygen vacancies rate and Mn3+ ratio, promoting H2O2 and glutathione degradation, producing more singlet oxygen under X-ray, increasing reactive oxygen species level, and alleviating hypoxia within the tumor microenvironment. It shows promising potential for anti-cervical cancer therapeutics.