A Smart Ru-Locked Chemiluminescence Probe via Bioorthogonal Activation for Highly Selective, Real-time and Non-Invasive In Vivo Imaging of Thiol Dysregulation

Bioorthogonal cleavage chemistry (BCC) has been extensively applied to fluorescence-based imaging in cancer diagnostics. Its potential in chemiluminescence imaging is to be explored. In this study, a smart ruthenium (Ru)-catalyzed bioorthogonal activa