医学
螺内酯
盐皮质激素受体
肾脏疾病
内科学
心脏病学
安慰剂
内分泌学
醛固酮
泌尿科
病理
替代医学
作者
Sanjay Rajagopalan,Mirela Dobre,Jean‐Eudes Dazard,Armando Vergara-Martel,Kim A. Connelly,Michael E. Farkouh,Juan Gaztañaga,Heather Conger,Ann M. Dever,Laleh Razavi-Nematollahi,Anas Fares,Gabriel Tensol Rodrigues Pereira,Jonnelle M. Edwards,Mark J. Cameron,Cheryl Cameron,Sadeer Al‐Kindi,Robert D. Brook,Bertram Pitt,Matthew R. Weir
出处
期刊：Circulation
[Lippincott Williams & Wilkins]
日期：2024-08-12
卷期号：150 (9): 663-676
被引量：1
标识
DOI：10.1161/circulationaha.123.067620
摘要
Persistent mineralocorticoid receptor activation is a pathologic response in type 2 diabetes and chronic kidney disease. Whereas mineralocorticoid receptor antagonists are beneficial in reducing cardiovascular complications, direct mechanistic pathways for these effects in humans are lacking.
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